Fen Phen Diet Pills was an anti-obesity pill (anorectic) which contained two drugs; Fenfluramine and Phentermine. Later on a related drug Dexfenfluramine was added. The term Fen-phen was coined in 1994 when Pietr Hitzig and Richard B. Rothman reported that this combination could reduce alcohol and Cocaine craving.
It was released in 1996 with no approval from Food and Drug Administration. It was marketed by American Home product (later known as Wyeth) as Pondimin, but was shown to cause potentially fatal pulmonary hypertension and heart valve problems. Wyeth created drugs sold as Redux and Pondimin, which were utilized as the fenfluramine half the fen-phen mix formula.
It suddenly became a hit because of its very efficient fat reduction results. However, it was discovered that it reduced weight temporarily and many people complained because of the side effects causing it to be ordered off the market by FDA in September 1997. Legal damages against Wyeth went well over $13 billion.
Fen-phen is no longer widely available. The phen in the name Fen Phen Diet Pills refers to a drug called phetermine, which wasn’t banned. Phentermine was not shown to induce any dangerous effects. The Fen-phen drugs were linked to heart valve problems. Reports suggested the drug caused valvular heart-disease, pulmonary hypertension, primary in women who had been undergoing treatment with fen-phen or dexfluramine.
These side effects were mixed with some connected to other diseases but many patients experienced shortness of breath, fainting and coughing up blood.
Qysmia was introduced as a new anti-obesity drug and was produced by Vivus Inc under supervision of Food and Drug Administration. It was meant to replace Fen-phen. However, many people did not know that it was repackaged Fen-phen, created using two older drugs: topiramate and phentermine.
It was officially referred as top-phen. The side effects of Qysmia included tingling in the hands and feet, constipation, dry mouth, dizziness and insomnia. Food and Drug Administration rejected Qysmia, then known as Qnexa, in 2010 because it was associated with elevated heart rate, psychiatric problems and birth defects. An overweight or obese person would be much better off simply switching to grass-fed meat than taking Qysmia.
Obese people who want to reduce weight may turn to herbal fen-phen which is easier to obtain than fen-phen ever was. As a dietary supplement, herbal Fen Phen Diet Pills is available without prescription in drugstores. The prescription combination consists of fenfluramine, which raises the level of the chemical serotonin in the brain.
This makes one feel full and eat less. Phenteramine, increases the metabolic rate so that the person burns up more calories. Herbal fen-phen is a combination of extracts of Saint-John’s wort, a mood-boosting herb, and ma huang, a stimulant also known as Ephedra. Herbal Fen-phen contains enough Ephedra to deliver between 40-60 milligrams of ephedrine alkaloid a day.
Phen375 was introduced in February 2009. On June 27th 2012, Food and Drug Administration approved the new diet pill Belviq (lorcaserin), by Arena pharmaceuticals. It is the first weight loss drug to be approved in 13 years.